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Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate
Researchers selecting a compound for a specific endpoint should match mechanism to model rather than treating these peptides as interchangeable
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A key redox-signaling pathway present in microglia is the NF-B pathway
It can present with skin reactions of dermatitis, acneiform eruption, dry skin, pruritus, photosensitivity, or hand-foot skin reactions in 28% to 71% of 30 patients
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