Bertolini S, Donati C, Elicio N, et al
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While these questions remain to be explored, insights from the present studies clearly imply new strategies to develop more effective ferroptosis-inducing therapies for the benefit of cancer patients
This leads to decreased peripheral and central 5-HT levels, impaired receptor function, reduced concentrations of tryptophan and 5-HT (232), worsened symptoms of affective disorders, elevated levels of tryptophan catabolites (233, 234), and increased concentrations of toxic metabolites in the CNS (235)