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The search for biological surrogate markers is underway, and there have been developments of positron emission tomography (PET) and single-photon emission computed tomography (SPECT) techniques, which have shown compelling correlations with PDs global severity [45]

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This copper peptide upregulates vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), both of which drive capillary sprouting