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Unlike sulfonylureas, which stimulate insulin secretion independently of blood glucose and can lead to hypoglycemia, GLP-1RAs improve glycemic control in a glucose-dependent manner, thereby minimizing the risk of hypoglycemia

Under normal conditions, acute administration of liraglutide did not alter cecal occludin and TNF- mRNA levels, but significantly increased cecal RegIII and IL-33 mRNA levels (Fig

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Unlike GLP-1RAs, DPP-4i have no effect on gastric emptying or weight loss

Recent work shows that blocking mitochondrial ROS or curbing Ca + influx protects cells against Xc - -inhibitor-induced ferroptosis (123, 124)