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Estrela JM, Ortega A, Obrador E
Consider: Baseline blood pressure and heart rate measurement before starting combination therapy Regular monitoring during dose titration of either medication Prompt evaluation of palpitations, chest pain, or shortness of breath Caution in patients with pre-existing cardiovascular disease , including coronary artery disease, arrhythmias, or uncontrolled hypertension ECG evaluation if indicated by clinical history or symptoms Nutritional adequacy must be maintained
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RACKER E (1953)
Laetitia Coassolo, the lead researcher on the study that discovered BRP, and her team believe that future investigation on the efficacy, safety, and long-term impacts of BRP should consist of large-scale clinical trials to validate BRPs safety and effectiveness across diverse populations
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