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Real-World Evidence & Gastrointestinal Mechanism Matrix Unlike the musculoskeletal dataset, the gastrointestinal reports showed gradual effects

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If haemorrhoids keep coming back or you have other symptoms like weight loss or ongoing bowel changes, its vital to get checked. Symptoms that require urgent medical assessment include: Persistent or unexplained bleeding Changes in bowel habits Abdominal pain Unintentional weight loss Some of these can overlap with serious conditions, including bowel cancer

Only half of 18- to 34-year-olds drank alcohol in 2025, down from nearly 60% two years earlier

& Polakof, S