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Ipamorelin is the amplifier: it opens a second gate so the same GHRH drive translates into a bigger release, while its selectivity keeps cortisol and prolactin largely out of the picture
Of those entering the study, 14 had normal renal function, 11 had mild RI, 11 had moderate RI, ten had severe RI, and ten had ESRD requiring hemodialysis
Understanding this progression helps patients persist through the difficult early weeks when side effects peak but results haven't arrived yet
The clearest evidence sits at the top of the staircase
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