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The synergistic effect of aromatic residues, arginine and negatively charged histidine can enhance the stability of enzyme binding, and the regulation of hydrophobic N-terminal residues on aging-related enzyme activities reveals a new optimization direction

Semaglutide, a GLP-1 receptor agonist approved for type 2 diabetes and weight management, is frequently prescribed alongside thyroid medications like levothyroxine

However, t max and t of digoxin were similar when administered with or without SNAC (Electronic Supplementary Table 2)

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Wang J, Bai X, Peng C, Yu Z, Li B, Zhang W, et al