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It is also a consistency challenge
However, evidence from research studies suggests that GLP-1 analogs may also reduce gastric acid secretion, which can impair the conversion of dietary B12 into its absorbable form and decrease binding to intrinsic factor, both of which are necessary for proper absorption
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Pickart and colleagues reported in Nature (1980) that the tripeptide facilitates copper uptake into cultured cells, and potentiometric titration places the GHK-Cu stability constant at log K of approximately 16.4, marginally above the copper transport site of human serum albumin at roughly 16.2
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