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57,58 Cystatin C-based eGFR (eGFRcys) is increasingly being adopted for detecting and staging CKD
The PDB structures with the following accession codes 2WCI, 3L4N, 3D4M, 3D5J, 2M80, 2WUL, 2WOU, 1MEK, 1B4Q and 4FIW were used in this work
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Because Cys20 oxidizes naturally as well as artificially, the C20S mutant was used for structural determination of the complexes
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