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The caloric deficit also means reduced protein availability for tissue synthesis, reduced micronutrient availability, and potentially reduced copper delivery to the enzymatic systems that GHK-Cus carrier function bypasses

This effect is thought to involve two main mechanisms

The peptides anxiolytic mechanism appears to involve favoring natural homeostasis of the GABA receptor complex and enhancing GABAergic transmission through distinct, non-benzodiazepine pathways

This is why the TGA in Australia in 2008 granted the peptide the classification of safe supplementary substance, an exceptional regulatory step for a molecule that failed in its primary indication

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