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Bupropion stimulates POMC neurons in the hypothalamus to reduce appetite, but the body has a natural feedback loop that can dampen this effect over time
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This makes it especially valuable for patients focused on recovery, sleep quality, or injury healing
adults currently use GLP-1 for weight loss Obesity rate: Declined from 39.9 percent (2022) to 36.4 percent (2026) based on self-reported BMI Diabetes diagnosis rate: Stable since 2023 after 15 years of gradual rise Important limitation: Self-reported data
Therapie 76(5):425433
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