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The combination of female sex, rapid weight loss, and GLP-1 use means right-upper-quadrant pain should prompt evaluation rather than self-management

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This tissue expansion process continues in phase 2, characterized by hormone responsiveness ( ESR1 , PGR ) and increased energy consumption (CKB , SCGB1D2 , HGD , IDO1 , ATP1A1 , PSAT1) [11] (Fig