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Acknowledgements This work was supported by the National Natural Science Foundation of China (U23A20573, U23A20140), S&T Program of Hebei (242Q4301Z, 236Z4306G, 23314401D), the Hebei Natural Science Foundation (E2024208084), Huangjintai plan project of Hebei provincial department of education (HJZD202512), and Basic Research Fund of Hebei University of Science and Technology (2025XL021)
None of this is individualized medical advice it is the documented research cadence
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