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It was developed as a stable analogue of -MSH (alpha-melanocyte-stimulating hormone) a hormone responsible for regulating melanin production in the skin
Interestingly, GLP-1RAs are known to reduce appetite and food intake partly via appetite-inhibitory neurotransmission signaling within the arcuate nucleus [16, 17], possibly resulting in subsequent improvements in insulin resistance and serum lipid profiles (e.g., reduction in triglyceride levels)
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