incretin and glp-1 hormones obesity - Alcaino - 2025 - The Journal of Physiology PDB-101: Molecule of the Month:

Evidence now extends to fatty liver disease, heart failure, and sleep apnea

Quality of evidence: II-B, Strength of recommendation: 1 Panel level of agreement: In total agreement 87%, in partial agreement 13% Patients with ALF, HE, and at risk for an increase in ICP should be managed in a calm environment, with serum sodium monitoring (maintaining levels between 140 and 145 mmol/l) and HE treatment with lactulose and rifaximin

Specifically, understanding the role of GLP-1 and GLP-1RAs in the neurologic, and by extension, neuro-ophthalmic systems is of particular interest and the focus of this review

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CTR-HEK 293 cells were transfected with polyethylenimine (PEI) as per manufacturers protocol using 1:6 (w:v) DNA:PEI ratio on 24-well plate