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It mimics the glucagon-like peptide-1 (GLP-1), a hormone that regulates blood sugar by stimulating insulin secretion and inhibiting glucagon release
Importantly, an additional experiment showed that LASSS-treated BSA (after the removal of un-reacted LASSS) exhibited nitration resistance to the optimal peroxynitrite-treatment (1:2000 ratio), as shown in supplementary Figure 2, suggesting a model that LASSS-induced chemical modification mechanism exerts a nitration-inhibitory effect on a wide range of proteins susceptible to tyrosine nitration
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Weight loss in this population must be carefully monitored to ensure that lean mass preservation is prioritized
Research has demonstrated its involvement in wound healing through enhanced collagen and decorin gene expression [1] , activation of tissue remodeling pathways [2] , and regulation of genes associated with antioxidant defense and anti-inflammatory responses [3] [4]
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