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Description

1921 Recently, a double-blind, placebo-controlled randomized clinical trial of phase I study of (in)GSH in PD ( n =30) demonstrated (in)GSH was safe and tolerable, and both active study arms demonstrated an improvement over placebo in total Unified PD Rating Scale scores, specifically in activities of daily living and motor Unified PD Rating Scale subscores

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Interestingly in PD patients, it has been shown, an specific increase in SOD levels in the substantia nigra, with no changes in activities of glutathione peroxidase, catalase and glutathione reductase (EC 1.8.1.7) [25]

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