When we ran her body composition analysis, we discovered she'd lost almost as much muscle as fat
As is typical for early-phase clinical trials, no formal statistical hypothesis testing or sample size calculation was performed
However, if the A1c is 60 mg/mmol, or progressive increase in UACR despite appropriate therapy, eGFR 30% increase in serum creatinine within 3 months of starting SGLT2i, ACEi, or ARB, inability to achieve target BP, or signs/symptoms of another underlying kidney disease, such as glomerulonephritis
You have ongoing constipation, reflux, or nausea thats reducing your food and fluids
Some women, particularly those on HRT, experience body recomposition where they lose fat but gain muscle, resulting in stable or even slightly increased weight despite clear improvements in measurements and clothing fit