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To our knowledge, no study assessed the potential of abuse of these medications anecdotally reported in anorexia or bulimia nervosa, which would require further investigation

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On February 5, 2024, the Amgen team published an article in the journal "Nat Metab," confirming the antagonistic activity of AMG 133 on GIPR and the agonistic activity on GLP-1R in cellular systems

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Project number: 6602c-TF/21-437 Ethics declarations Ethical approval The study was designed and conducted according to ethical norms approved for animals

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