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Nausea and diarrhea were the most common side effects which were transient and improved with time, with less than 5% of the patients in the treatment group discontinuing treatment from gastrointestinal side effects

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Magouliotis DE, Tasiopoulou VS, Svokos AA, Svokos KA, Chatedaki C, Sioka E, Zacharoulis D

244 Therefore, a complex regulatory mechanism may underlie the modulation of TMAO metabolism by statins, necessitating further research to clarify the precise pathways involved and their clinical implications (Table 8)

When the bodys temperature rises, the hypothalamus triggers mechanisms to cool it down, such as sweating and increasing blood flow to the skin