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The additional content of clinical features of specimens are showed in Supplementary Table 1

Below 3.0 mEq/L requires urgent medical intervention

Dna damage following combination of radiation with the bioreductive drug aq4n: possible selective toxicity to oxic and hypoxic tumour cells

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Consider treatment response and tolerability when selecting the maintenance dosage Cardiovascular risk reduction maintenance dose: Either 2.4 mg (recommended) or 1.7 mg once weekly, based on patient response and tolerance