NEDA cautions that for people with active eating disorders or a history of disordered eating, these drugs can be harmful when not used for their intended purpose, when inadequately monitored or monitored by clinicians without eating disorder expertise, or when used for weight loss motivated by weight stigma. That doesnt mean GLP-1s are automatically off the table, but it does mean that this decision warrants extra care, specialist input, and close monitoring throughout
The studies were brief, with the first involving one of four ascending single doses over 28 days, and the second involving two or three weekly or biweekly doses over 49 days [2]
Activation of this pathway regulates gut responses, including intestinal transit time, motility, absorption rates, and nutrient exposure of enteroendocrine cells
Halder and Bridgeman-Shah
Instead of trying to do everything at once, make smaller, more consistent changes instead