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Furthermore, the requirement for patients to have an available weight measurement on the index date and after 1 year of follow-up and to be persistent on therapy for 1 year may have introduced potential selection bias in favor of patients who are more actively managed and/or for whom treatment is effective
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The result is stronger, more functional tissue
This option could be of preference in women with metabolic or cardiovascular conditions that contraindicate the use of estroprogestins [60]
Who Is Most Likely to See Hormonal Effects
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