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The triple-agonist combination filings suggest AstraZeneca is positioning either for a combination-product strategy (a triple agonist co-formulated or co-packaged with an SGLT2 inhibitor, an amylin analog, or a calcitonin/amylin dual like cagrilintide) or for a licensing-target role where the combination claims would apply to partner products

Semaglutide Versus Dulaglutide Once Weekly in Patients With Type 2 Diabetes (SUSTAIN 7): A Randomised, Open-Label, Phase 3b Trial

Site guidance follows the DailyMed pen label for this Phase 3 compound

It requires frequent testing of eye pressure, monitoring of visual field loss, and optic nerve evaluations

Compounded semaglutide is produced by compounding pharmacies using the same active ingredient but is not FDA-approved