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Research shows significant weight regain when semaglutide is discontinued, with participants in the STEP 4 trial regaining approximately two-thirds of lost weight within one year of stopping medication
After that, it gradually tapers as the body adapts to slower gastric emptying
If you are participating in a clinical trial involving retatrutide, you should also contact your research team or trial investigator promptly if you experience any of the above symptoms, in accordance with the trial protocol
The appetite suppression deserves special attention
Further re-excision may be necessary
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