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Primary outcome events occurred in 14.6% and 16.6% of semaglutide and placebo subjects, respectively, who used SGLT2i at baseline or initiated it during the trial
The important caveat is that Retatrutide remains in Phase 3 trials and has not yet received prescription approval in Canada or the US
Stopping or interrupting GLP-1s for 6 months or more raised the risk for adverse cardiovascular events
Marquez-Meneses JD, Olaya-Bonilla SA, Barrera-Carreo S, et al
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