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85 A randomized controlled trial in 769 infertile men with low sperm numbers and MTHFR polymorphisms found, in those with the MTHFR 677 TT genotype, 800 mcg (1,360 mcg DFE) folic acid daily for three months improved semen parameters and sperm fragmentation
Traditional treatments like NSAIDs and corticosteroids provide temporary relief but come with significant drawbacks
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A.GonzalezF
The safety assessment draws from each compound's independent safety profile, mechanistic non-overlap, and growing clinical experience from physicians who prescribe both
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