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Enzymatic conjugation of chlorambucil with glutathione by research-subject glutathione S-transferases and inhibition by ethacrynic acid

10.1016/j.freeradbiomed.2013.05.001 97 SonY.CheongY

Glutathione (GSH) is the primary antioxidant defense molecule in the brain [12]

Kinetic analysis of Arabidopsis GCL showed that the enzyme was inactivated by buthionine sulfoximine, a potent inhibitor of mammalian GCL, and used a random ter-reactant kinetic mechanism with a preferred order of binding for catalysis (Jez et al., 2004)

On a U-100 insulin syringe, 250 g (0.25 mg) of BPC-157 equals 12.5 units when reconstituted at 5 mg / 2.5 mL (2 mg/mL concentration)