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Nat Rev Cancer 16 , 345358 (2016)

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To Raufman's surprise, in 1981 he discovered that when he put one of the peptides onto guinea pig pancreata, it caused a sharp rise in amylase, an enzyme made in the pancreas and salivary glands in the mouth to help the body break down carbohydrates (Raufman, Tensen, Sutliff

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16-OH-E1 is a precursor to estriol, a weak estrogen hormone

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