Nature 372:425432 Heymsfield SB, Greenberg AS, Fujioka K et al (1999) Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial
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Other compounds like GHRP-2 and GHRP-6 might be administered 13 times daily, with some protocols emphasizing spacing them out from meals to maximize efficacy