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The honest limit on that record is that it is uncontrolled, and the single controlled read was underpowered

The weight loss is driven substantially by appetite suppression and reduced caloric intake

doi: 10.1007/978-981-13-2835-0_15 4 BlountBCMackMMWehrCMMacGregorJTHiattRAWangGet al

it's a specialized blend designed to investigate the pathways governed by the Klotho gene, which is often called a 'master regulator' of the aging process

Because it hasn't gone through rigorous clinical trials, we just don't know what a safe dose is, what the short-term side effects are, or what the long-term health consequences could be