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The valproic acid rat model of autism presents with gut bacterial dysbiosis similar to that in human autism
its core role is derived from its unique biphenyl methyl structure, which enables it to specifically target and regulate the PI3K/Akt/mTOR signaling pathway (10)
Pilkington et al
10.1080/10715760100301181 21 ForcinaG
Interestingly, studies have shown that the cytotoxicity of ZnO nanoparticles is not dependent on the levels of soluble Zn 2+ ions in the extracellular component of the culture medium but due to the direct contact with the cells or uptake by the cancer cells [211]
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