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As a defined small molecule, 5-Amino-1MQ is a "tool compound" in the classical pharmacology sense useful for probing NNMT biology specifically
Research shows that low serum vitamin B-12 levels are linked to decreased bone density, which can lead to fragile bones and a higher risk of osteoporosis
Research shows that increased NNMT is strongly associated with obesity, so targeting this enzyme could be beneficial for weight loss [2]
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