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SGLT2-i induced natriuresis and glomerular hemodynamics changes resemble, even partially, those observed with sacubitril/valsartan, a first in-class angiotensin receptor neprilysin inhibitor (ARNi)

Hence, weight gain was suggested to be the result of OSA improvement following the initiation of CPAP therapy

All week 48 analyses were prespecified in the statistical analysis plan, and all week 72 analyses were considered post hoc

With its once-weekly dosing option and notable reductions in HbA1c levels, semaglutide has become a cornerstone in diabetes management, earning approval for both cardiovascular and renal benefits

Many patients who were waiting for an oral anti-obesity pill for convenience reasons will naturally gravitate toward what they already know works