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In a 24-week trial involving more than 500 participants, AOD-9604 failed to induce significant weight loss
Reduces oxidative stress and cell damage
A meta-analysis of 8 RCTs found that NAC supplementation significantly reduced fasting glucose (WMD: -5.84 mg/dL) and HbA1c (WMD: -0.27%) in people with metabolic conditions (Sarkaki et al., Clin Nutr ESPEN, 2021) [57]
Reactive oxygen-responsive organic polymers (mPEG-TK-PLGA) were prepared by copolymerization of thioacetalinker with PEG and PLGA, which were used to load triphenylphosphine (TPP)-modified cerium nanoparticles and atorvastatin (ATV/PTP-TCeria NPs)
Johny et al., 2021)
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