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This includes: Structured dietary programmes such as low-calorie or very-low-calorie diets under dietitian supervision Increased physical activity tailored to individual capabilities, aiming for at least 150 minutes of moderate-intensity activity weekly Behavioural therapy addressing psychological factors contributing to weight gain Commercial weight management programmes (such as Weight Watchers, Slimming World) which NICE recognises as potentially effective options for some people Specialist interventions: NICE guidance recommends considering bariatric/metabolic surgery for people with a BMI of 40 kg/m or more, or between 35-40 kg/m with significant weight-related comorbidities

-TOH interrupts this chain reaction by donating a hydrogen atom to neutralize ROO, forming the tocopheroxyl radical (-TO) and halting lipid peroxidation

PMID: 34798060

However, the cost of Semaglutide can be a critical factor for individuals considering this medication