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Semaglutide belongs to a class of medications known as GLP-1 receptor agonists (glucagon-like peptide-1)

Tomich CE, Zunt SL

High-fat and fried foods can worsen nausea, bloating, and delayed digestion due to prolonged gastric emptying

The most common side effects of tirzepatide are gastrointestinal: Nausea: Reported by 12-33% of participants depending on dose (most common early in treatment) Diarrhea: 12-21% of participants Constipation: 6-11% of participants Vomiting: 5-13% of participants Decreased appetite: Expected therapeutic effect but can be uncomfortable These side effects are typically most intense during the first few weeks at each new dose level and tend to improve as the body adjusts

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