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(Arumugasaamy et al., 2019) found that both fluoxetine and sertraline slowed calcium oscillations in cardiomyocytes, inducing the increased secretion of troponin T and creatine kinase-MB, while also decreasing the secretion of N-terminal prohormone of brain natriuretic peptide (NT-proBNP), all three of which are key biomarkers of cardiac injury

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Five years later, it partnered with Lilly to develop pramlintide, an amylin analog for the treatment of diabetes