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Unlike semaglutide, which targets only GLP-1 receptors, tirzepatide works on two key systems in your body instead of just one

Figure 4: Changes in body weight in A) lean mice and B) obese mice and changes in food intake in C) lean mice and D) obese mice, across the three different experimental treatment groups

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Most people dont get results immediately, but many feel a difference in their energy or sleep within eight weeks, while larger impacts on muscle tone or mood tend to appear around three months