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The exposure-adjusted incidence rate for treatment-emergent adjudication-confirmed pancreatitis in the pooled clinical studies for OSA (Studies 5 and 6) was 0.84 patients per 100 years for ZEPBOUND and 0 for placebo-treated patients

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Nearly 50% of participants were also hospitalized or had visited and urgent care for worsening heart failure in the 12 months prior to the study

Someone who has already completed the titration phase, knows their effective dose, and is continuing at a stable level does not need the same level of provider support as someone starting for the first time

Although skeletal effects are beneficial in preclinical investigations, clinical evidence on fracture risk is still uncertain