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5 Overview of different long-chain fatty acid oxidation disorders 5.1 Disorders of carnitine transport 5.1.1 Primary carnitine deficiency / organic cation transporter 2 (OCTN2) deficiency / carnitine transporter disorder (CTD) Clinical presentation Patients with systemic primary carnitine deficiency (also known as OCTN2 deficiency or CTD

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Research has shown increased phosphorylation of extracellular signal-regulated kinases (ERK) 1 and 2, along with their downstream targets, including c-Fos, c-Jun, and Egr-1, which are molecules involved in cell growth, migration, and angiogenesis

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