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Furthermore, it has emerged that supporting or inducing mitochondrial bioenergetics, stress responses, mitophagy, and other adaptation mechanisms is critical to mediate some of the health or longevity benefits observed in studies using NAD + modulation strategies

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doi: 10.1016/J.SCITOTENV.2021.146264 99

Higher concentrations (5mg/mL) reduce injection volume but demand more precise syringe measurement a 250mcg dose at 5mg/mL requires only 0.05mL, which is near the limit of reliable measurement