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Unlike currently available GLP-1 drugs (glucagon-like peptide 1) including semaglutide, sold as Ozempic and Wegovy, aleniglipron is a small-molecule drug that is taken orally and is currently in development for the treatment of obesity

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After 72 h treatments, 0.5 g ml 1 propidium iodide (Sigma-Aldrich, P4864) and 1.4 g ml 1 Hoechst 33342 (Invitrogen, H3570) were added to cells

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The trial is divided into four arms, each with a distinct donanemab dose

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Your doctor may choose one based on your medical history, heart function, or any coexisting conditions like diabetes or heart failure

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