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Any meaningful comparison between semaglutide and tirzepatide requires both to be at steady state
Higher concentration of fatty acids (lipids)
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AMPK also inhibits lipid biosynthesis by suppressing transcription factor sterol regulatory element-binding protein 1 (SREBP1) and promoting the action of peroxisome proliferator-activated receptor alpha (PPAR), a nuclear receptor that acts to enhance both mitochondrial and peroxisomal FA -oxidation 23
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