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To determine whether the signals share the same causal variant, we applied co-localization analysis 17 and found that the signals co-localize with high probability (BMI % versus nausea, H4 = 96.6%
Nguyen T, Yang CS, Pickett CB (2004) The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress
Conclusion Dark lips are common and usually harmless
Shifts fluid and electrolyte handling in the bowel
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