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Zinc plays an important role in ammonia metabolism and its detoxification in the liver.24,25 Other factors that contribute to the development of HE are lactate and excess manganese.26 7 HE is characterized by neurologic, neuropsychiatric, and musculoskeletal alterations, whose clinical presentation is variable and heterogeneous
Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing sp1 glycosylation
Journal of neurosurgical sciences
T., Sonne, N., Andreassen, K
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