Pycnogenol showed effects to stop further progression of retinopathy and ameliorate the eyesight of diabetics by stabilizing and sealing leaky capillaries of the retina, stopping further outflow of blood ( In an RDP study, Pycnogenol was shown to reduce capillary leaking in the eyes ( supplementation for two months, the ophthalmoscopy score significantly improved by 9% in the left eyes and by 17% in the right eyes compared to baseline, whereas there was no change observed in the placebo group
Footnotes Conflicts of interest No potential conflict of interest relevant to this article was reported
Category 2 of the Bulk Substances Nominated Under Sections 503A or 503B of the Federal Food, Drug, and Cosmetic Act Park MG, Yeo JK, Park SG, Na W, Moon DG
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Isothiocyanates have been found to inhibit HDAC expression and/or activity in cultured cancer cells (38-43)