Permanent discontinuation of treatment only occurred in one participant receiving 1.2 mg of cagrilintide, one participant receiving 2.4 mg of cagrilintide, and one participant that developed a case of pancreatitis after administration of liraglutide
However, it never received FDA approval because the results, while positive, weren't dramatic enough to meet regulatory thresholds for an obesity drug
Dorr RT, Lines R, Levine N, Brooks C, Xiang L, Hruby VJ, Hadley ME
Our reference on whether current evidence supports tirzepatide as a breakthrough diabetes therapy reviews this record in depth
Astrocyte-associated axonal damage in pre-onset stages of experimental autoimmune encephalomyelitis