Patients with ALS tend to have higher levels of oxidized glutathione (glutathione that has already been used to protect the body from free radicals) (Baillet 2010)
The results highlight the considerable capability of the DNZ-NLPs to traverse the BBB, a feature that is critical for the development of therapeutic strategies aimed at neurodegenerative disorders such as HD, offering promising implications for the treatment of central nervous system diseases
Author contributions ZS: Writing original draft, Writing review & editing, Data curation, Investigation, Methodology, Project administration, Validation
Oral GHK-Cu is more convenient but faces significant absorption challenges due to enzymatic degradation in the digestive tract
Researchers are developing more efficient formulations, such as long-acting and oral versions, to improve patient compliance and outcomes